Arbutus v Moderna lawsuit explains how mRNA encapsulated in “LNPs” (lipid nanoparticles) travels throughout body, Exposes CDC lie of staying at injection site
Arbutus v Moderna lawsuit explains how mRNA encapsulated in “LNPs” (lipid nanoparticles) travels throughout body, Exposes CDC lie of staying at injection site
From Arbutus v Moderna.
“INTRODUCTION
1. The impact of the COVID-19 pandemic, one of the greatest public health challenges in modern history, would be immeasurably worse but for the rapid, widespread availability of cutting-edge mRNA-based vaccines like Moderna’s. Moderna brought its vaccine from lab bench to arms in record speed. That unprecedented accomplishment was made possible by Moderna’s use of breakthrough technology Arbutus had already created and patented—a revolutionary lipid nanoparticle (“LNP”) delivery platform that took the scientists of Arbutus years of painstaking work to develop and refine. Moderna was well aware of Arbutus’s LNP patents and licensed them for other product programs, but it chose not to do so for its COVID-19 vaccine. Instead, it attempted to invalidate several of the patents before the United States Patent and Trademark Office, and when those efforts largely failed, Moderna simply used the patented technology without paying for it or even asking for a license. Plaintiffs do not seek an injunction or any relief in this case that would impede the sale or manufacture of Moderna’s life-saving vaccine. They seek only fair compensation for the use of patented technology they developed with great effort and at great expense, without which Moderna’s COVID-19 vaccine would not have been successful.
2. Medicines using messenger ribonucleic acid (or “mRNA”) technology, like Moderna’s COVID-19 vaccine, rely on synthetic mRNA that enters the body’s cells and instructs them to make proteins they would not necessarily make on their own. Moderna’s COVID-19 vaccine, in particular, uses mRNA to cause cells to make a small piece of the virus that causes COVID-19 called the “spike protein.” That small piece, which is harmless in isolation, prompts the body’s immune system to produce antibodies that will recognize the spike protein if it is encountered in the future and destroy it. In this way, the vaccine equips a person’s body ahead of time with antibodies to fight the COVID-19 virus if that person experiences a subsequent exposure.
3. Ever since the vast potential for mRNA-based vaccines and other mRNA-based medicines began to catch the attention of scientists more than two decades ago, the biggest technological hurdle to developing and deploying them has been devising a safe and effective way to deliver the mRNA to the cell. Without adequate protection, mRNA quickly degrades in the body. For mRNA vaccines like Moderna’s to work, they must incorporate a mechanism for protecting the fragile mRNA, delivering it through cell membranes, and then releasing it inside the cell. In the words of one Nobel Prize winning scientist, the secret for making RNA-based products work has always been “delivery, delivery, delivery.”1
4. Having vexed experts in the field for years, that problem eventually found a solution in the innovative research of Arbutus scientists. Their solution was ingenious: microscopic particles built from four carefully selected types of fat-like molecules, so small that they are measured in nanometers but still stable enough to shelter and protect an RNA molecule on a voyage through the human body to a target cell, and then through the target cell’s membrane, before finally releasing the RNA. These tiny fat-like particles are called “lipid nanoparticles,” or “LNPs.” The United States Patent and Trademark Office has granted Arbutus several patents for its groundbreaking LNP technologies.”
Further evidence CDC lied, Part 2 Australian peer reviewed study, vaccine disperses rapidly from the injection site and can be found in nearly all parts of the body
“The mRNA vaccines were supposed to remain at the injection site and be taken up by the lymphatic system. This assumption proved to be wrong. During an autopsy of a vaccinated person that had died after mRNA vaccination it was found that the vaccine disperses rapidly from the injection site and can be found in nearly all parts of the body [1]. The mRNA is enveloped in liquid nano particles (LNP) containing a mixture of phospholipids, cholesterol, PEGylated lipids and cationic or ionizable lipids [2]. Research has shown that such nanoparticles can cross the blood-brain barrier [3] and the blood-placenta barrier [4], so it came as no surprise that the European Medicines Agency assessment report for the Moderna vaccine on page 47 (https://www.ema.europa.eu/en/documents/ assessment-report/spikevax-previously-covid-19-vaccinemoderna-epar-public-assessment-report_en.pdf) also noted that mRNA could be detected in the brain following intramuscular administration at about 2% of the level found in plasma. In 2021 researchers from Japan reported a disproportionately high mortality due to cerebral venous sinus thrombosis and intracranial haemorrhage. Despite not being able to prove a causal link with vaccines, as no autopsies were performed, they still believed that a link with vaccination is possible and further analysis is warranted [5].”
